Three years into its implementation, the EU Mission on Adaptation to Climate Change continues to drive climate resilience across Europe, uniting over 400 regional and local authorities. This 2025 report outlines the Mission's achievements and future directions, highlighting on-the-ground actions that translate strategy into impact. CARDIMED contributes to this progress through its innovative work in the Mediterranean region, focusing on Nature-based Solutions and regional collaboration for climate adaptation. The report underscores the importance of empowering local actors, managing climate risks, and aligning policy with practice—laying the groundwork for the upcoming European Climate Adaptation Plan.